eng Ansari Education and Research Society Journal of Ultra Scientist of Physical Sciences December 2009 21 3 699 706 jusps-B 1186 article MOHD. ASPOLLAH HJ. SUKARI 1 NEOH BEE KEAT 2 TANG SOOK WAH 3 Sugeng Riyanto 3 NORDIN HAJI LAJIS 1 GWENDOLINE EE CHENG LIAN 1 Department of Chemistry, Faculty of Science, University Putra Malaysia, 43400 Serdang, Selangor (Malaysia) Sime Darby Technology Centre, 2, Jalan Tandang 460 050 Petaling Jaya, Selnagor (MALAYSIA) Faculty of Pharmacy, Gadjah Mada University, Yogyankarta (INDONESIA) <p style="text-align: justify;">Phytochemical study on the rhizomes of <em>Kaempferia rotunda</em> originated from Yogyakarta, Indonesia has led to the isolation of crotepoxide, benzoic acid, tetracosanoic acid, b-sitosterol and stigmasterol. Tetracosanoic acid and benzoic acid have never been reported for this species previously. Bioactivity studies on the extracts and isolated compound (crotepoxide) were carried out. Extracts and crotepoxide from <em>K. rotunda</em> were not active against HL-60 (human promyelocytic leukemic) cell line in cytotoxic testing. However, the non-polar extract demonstrated moderate inhibition in antimicrobial assay whereas in FTC antioxidant testing, all extracts exhibited strong activity as compared to vitamin E.</p> <p>&nbsp;</p> <p>&nbsp;</p> https://ultraphysicalsciences.org/paper/1186/ Kaempferia rotunda Zingiberaceae antioxidant antimicrobial