<?xml version="1.0"?>
<records>
  <record>
    <language>eng</language>
    <publisher>Ansari Education and Research Society</publisher>
    <journalTitle>Journal of Ultra Scientist of Physical Sciences</journalTitle>
    <issn/>
    <eissn/>
    <publicationDate>August 2008</publicationDate>
    <volume>20</volume>
    <issue>2</issue>
    <startPage>335</startPage>
    <endPage>346</endPage>
    <doi>jusps-B</doi>
    <publisherRecordId>1309</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">Synthesis of Fluoro Substituted Benzothiazoles Incorporated with 1,3,4-Thiadiazoles for Biological and Pharmacological Screening</title>
    <authors>
      <author>
        <name>Gangadhar Shaw,</name>
        <affiliationId>1</affiliationId>
      </author>
      <author>
        <name>G.M. Sreenivasa </name>
        <affiliationId>1</affiliationId>
      </author>
      <author>
        <name>E. Jayachandran</name>
        <affiliationId>1</affiliationId>
      </author>
    </authors>
    <affiliationsList>
      <affiliationName affiliationId="1">P.G. Department of Pharmaceutical Chemistry, S.C.S. College of Pharmacy, Harapanahalli - 583131 (INDIA)</affiliationName>
    </affiliationsList>
    <abstract language="eng">&lt;p style="text-align: justify;"&gt;Various substituted 2[5&amp;#39;-(3-Methyl benzene)-1&amp;#39;,3&amp;#39;,4-thiadiazol-2&amp;#39;-yl amino)-6-flouro-7substituted (1,3) benzothiazoles and 2[5&amp;#39;-(p-chlorobenzene)-1&amp;#39;,3&amp;#39;,4&amp;#39;-thiadiazole-2&amp;#39;-yl amino) -6-fluoro-7substituted (1,3) benzothiazole containing different functional groups have been synthesized by condensing hydrazine hydrate with substituted 2-aminobenzothiazole in presence of ammonia, carbon disulphide with ethanol and sodium chloroacetate. Further it is treated with various aromatic acid (p-chloro benzoic acid and 3-methyl benzoic acid) in presence of pyridine. The identity of compounds were confirmed on the basis of their spectral (UV, IR, 1H NMR and MASS) data. Further, they have been screened for their antimicrobial, anti-inflammatory and anticonvulsant activities.&lt;br /&gt;&#xD;
&amp;nbsp;&lt;/p&gt;&#xD;
</abstract>
    <fullTextUrl format="html">https://ultraphysicalsciences.org/paper/1309/</fullTextUrl>
    <keywords>
      <keyword language="eng">Fluorine</keyword>
    </keywords>
    <keywords>
      <keyword language="eng">Benzothiazole</keyword>
    </keywords>
    <keywords>
      <keyword language="eng">Thiadiazole,</keyword>
    </keywords>
  </record>
</records>
