<?xml version="1.0"?>
<records>
  <record>
    <language>eng</language>
    <publisher>Ansari Education and Research Society</publisher>
    <journalTitle>Journal of Ultra Scientist of Physical Sciences</journalTitle>
    <issn/>
    <eissn/>
    <publicationDate>December 2008</publicationDate>
    <volume>20</volume>
    <issue>3</issue>
    <startPage>581</startPage>
    <endPage>586</endPage>
    <doi>jusps-B</doi>
    <publisherRecordId>1343</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">Toxicity of n-Hexane in extracted soybean meal : A Histopathological study on lungs of albino rats</title>
    <authors>
      <author>
        <name>SHABNAM FAIYAZ</name>
        <affiliationId>1</affiliationId>
      </author>
      <author>
        <name>HUMA ALI</name>
        <affiliationId>2</affiliationId>
      </author>
      <author>
        <name>MEGHA JHA</name>
        <affiliationId>2</affiliationId>
      </author>
      <author>
        <name>ASHISH MANIGAUHA</name>
        <affiliationId>2</affiliationId>
      </author>
      <author>
        <name>N. GANESH</name>
        <affiliationId>2</affiliationId>
      </author>
      <author>
        <name> J.D. AHI</name>
        <affiliationId>3</affiliationId>
      </author>
    </authors>
    <affiliationsList>
      <affiliationName affiliationId="1">Department of Zoology, Govt. M.V.M., Bhopal (M.P.) (INDIA)</affiliationName>
      <affiliationName affiliationId="2">Department of Research, Jawaharlal Nehru Cancer Hospital &amp; Research Center, Idgah Hills, Bhopal (INDIA)</affiliationName>
      <affiliationName affiliationId="3">Department of Zoology, Dr. Hari Singh Gour, University, Sagar (M.P.) INDIA</affiliationName>
    </affiliationsList>
    <abstract language="eng">&lt;p style="text-align: justify;"&gt;In extraction process of soyabean, soyameal obtained as a by-product. In this process n-Hexane has vital role, n-Hexane separates the complete oil contents of soya. Despite this vital function of n-Hexane, it is also known as health hazard compound. From the meal n-Hexane is metabolized into gamma diketone 2,5-hexanedione (2,5 HD), which binds with the lysine residues of neurophilament protein causing toxicological implication . The solvents &lt;em&gt;n&lt;/em&gt;-hexane exposure, the following four metabolites, 2-hexanol, 2,5-hexanedione, 2,5-dimethylfuran and g-valerolactone, were identified. 2,5-Hexanedione was the main &lt;em&gt;n&lt;/em&gt;-hexane metabolite found in previous study. n-Hexane in animals is a neurotoxic agent, also seems to be responsible for the neuropathies. Results suggest that the feeding of soybean containing up to 120 ppm &lt;em&gt;n&lt;/em&gt;-Hexane and inhalation of n-Hexane is toxic from 30 ppm to120 ppm.&lt;br /&gt;&#xD;
&amp;nbsp;&lt;/p&gt;&#xD;
</abstract>
    <fullTextUrl format="html">https://ultraphysicalsciences.org/paper/1343/</fullTextUrl>
    <keywords>
      <keyword language="eng">Soybean</keyword>
    </keywords>
    <keywords>
      <keyword language="eng">n-Hexane</keyword>
    </keywords>
    <keywords>
      <keyword language="eng">neurotoxic agent. </keyword>
    </keywords>
  </record>
</records>
