Synthesis of bioactive molecule fluoro substituted benzothiazoles comprising sulphonamido quinazolinyl imidazole for biological and pharmacological screening
Various substituted 3 (7-substituted-6-fluoro-1,3-benzothiazole-2yl)-1-[(4-methylphenyl)sulfonyl]-2-thioxo-2,3-dihydroquinazolin-4 (1H)-one and 2-[(4Z)-4-benzylidine-2-phenyl-5-oxo-4,5-dihydro-1H-imidazole-1-yl]-N-(7 -substituted-6-fluoro-1,3-benzothiazole-2-yl) benzamide. Containing different functional groups have been synthesized by condensing Ethylchloroformate with substituted 2-aminobenzothiazoles in presence of anhydrous K2CO3. The identity of compounds were confirmed on the basis of their spectral (UV-Visible, IR, 1H NMR and Mass) data. Further, they have been screened for their antimicrobial, antiinflammatory, anticonvulsant and anthelmentic activities.
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S. Patel; G. Sreenivasa; E. Jayachandran; N. Ghose; K. J. Kumar, "Synthesis of bioactive molecule fluoro substituted benzothiazoles comprising sulphonamido quinazolinyl imidazole for biological and pharmacological screening", Journal of Ultra Scientist of Physical Sciences, Volume 20, Issue 2, Page Number 281-296, 2018Copy the following to cite this URL:
S. Patel; G. Sreenivasa; E. Jayachandran; N. Ghose; K. J. Kumar, "Synthesis of bioactive molecule fluoro substituted benzothiazoles comprising sulphonamido quinazolinyl imidazole for biological and pharmacological screening", Journal of Ultra Scientist of Physical Sciences, Volume 20, Issue 2, Page Number 281-296, 2018Available from: http://ultraphysicalsciences.org/paper/1301/
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