In extraction process of soyabean, soyameal obtained as a by-product. In this process n-Hexane has vital role, n-Hexane separates the complete oil contents of soya. Despite this vital function of n-Hexane, it is also known as health hazard compound. From the meal n-Hexane is metabolized into gamma diketone 2,5-hexanedione (2,5 HD), which binds with the lysine residues of neurophilament protein causing toxicological implication . The solvents n-hexane exposure, the following four metabolites, 2-hexanol, 2,5-hexanedione, 2,5-dimethylfuran and g-valerolactone, were identified. 2,5-Hexanedione was the main n-hexane metabolite found in previous study. n-Hexane in animals is a neurotoxic agent, also seems to be responsible for the neuropathies. Results suggest that the feeding of soybean containing up to 120 ppm n-Hexane and inhalation of n-Hexane is toxic from 30 ppm to120 ppm.